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{
  "profile": { "sensitivities": ["Migraine"] },
  "location": { "lat": 51.5074, "lon": -0.1278 },
  "exposure_window_hours": 24,
  "mode": "agentic",
  "enrichment": {
    "condition_subtype": "episodic migraine",
    "known_triggers": ["barometric pressure change", "frontal passage"]
  }
}

{
  "kind": "vasus#insightResponse",
  "api_version": "1.6",
  "insight": {
    "risk_level": "Moderate",
    "summary": "A rapid frontal passage is driving a 6.2 mb barometric pressure drop over the next 24 hours, with pressure volatility elevated across the 72-hour window — a pattern repeatedly associated with migraine onset in the weather-sensitivity literature.",
    "key_mechanisms": [
      "Barometric pressure drops above 5 mb within 24h are associated with increased migraine onset in weather-sensitive patients",
      "Sustained pressure volatility across a 72h window compounds trigger likelihood"
    ],
    "recommendations": [
      "Surface the insight on the morning dashboard, ahead of symptom onset",
      "Prompt the user to log activity and sleep while the front passes"
    ]
  },
  "top_matches": [
    {
      "pmid": "28332220",
      "title": "Barometric pressure and migraine: meta-analysis of 7 studies",
      "journal": "Headache",
      "year": 2017
    },
    {
      "pmid": "25735484",
      "title": "Weather sensitivity in migraineurs",
      "journal": "Journal of Neurology",
      "year": 2015
    }
  ]
}